Mississippi
State Facts
Deaths, or 54.1% of all overdose deaths in the year ending April 2025 involved opioids.¹
Claims, or 4.2% of all Medicare Part D claims were for opioids in 2023 – an average of 71 per prescriber.²
Opioid prescriptions were dispensed in Mississippi in 2024 – an average of 6,028 prescriptions every day.³
The estimated total societal cost of opioid use disorder (OUD) in Mississippi in 2024.⁴
Opioid Settlement Funds
National approved use: providing support for non-opioid pain treatment alternatives, including training providers to offer or refer to multi-modal, evidence-informed treatment of pain.
Member & Endorser Footprint
Co-Sponsors (119th)
Rep. Michael Guest (R-MS-3)
Sen. Cindy Hyde-Smith (R-MS)
Rep. Mike Ezell (R-MS-04)
2025 Introduced Relevant Legislation
HB 1389
Ensures that no nonopioid drug approved byFDA for treatment or managment of pain will be disadvantaged or discouraged with respect to coverage relative to any opioid.
Introduced
01/20/2025Plan Impact
MedicaidVoices Letters
SB 2386 Gov. Policy Director Letter of Support
SB 2386 Gov. Chief of Staff Letter of Support
SB 2386 Gov. Legislative Director Letter of Support
1. Centers for Disease Control and Prevention (2025). Provisional Drug Overdose Death Counts. https://www.cdc.gov/nchs/nvss/vsrr/drug-overdose-data.htm
2. Centers for Disease Control and Prevention (2025). Medicare Part D Opioid Prescribing Mapping Tool. https://cms-oeda.maps.arcgis.com/apps/MapSeries/index.html?appid=5390718d875d4c049b1ac5976a9ff083
3. The Mississippi Opioid and Heroin Data Collaborative (2025). Provisional Data Report Calendar Year 2024. https://msdh.ms.gov/msdhsite/_static/resources/21209.pdf
4. Avalere Health (2025). The cost of addiction: Opioid use disorder in the United States. https://advisory.avalerehealth.com/wp-content/uploads/2025/05/Avalere-Health-White-Paper_The-cost-of-opioid-addiction_OUD-in-the-United-States.pdf